Pyromaniac

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Pyromaniac is a Special passive item.

Effects

+5 bombs
All explosions heal Isaac for one red heart instead of damaging him. If Isaac has no red heart containers or full health, no damage is taken.

Makes the player immune to Mom's, Satan's, and other enemies' stomp attacks, making those fights substantially less difficult.
- Due to the immunity to Mom's stomping attack, Mom's Toenail has improved usefulness.
Makes the player immune to The Cage's, The Adversary's, and Mega Satan's rock wave attack.
The item is unable to produce Soul Hearts, Black Hearts, or Eternal Hearts, making Pyromaniac a little less effective if used with ??? or The Lost. However, these characters still gain immunity to explosions.
Makes the player immune to fires left behind by enemies and their hot bombs, as well as projectiles from Red and Purple Fireplaces but not the fireplaces themselves.
Ultra Greed's second form in Greedier Mode uses explosive attacks almost exclusively. As a result, Pyromaniac makes characters nearly invulnerable against him.

Dr. Fetus/Epic Fetus/Ipecac: Explosions heal Isaac, essentially making him invincible as long as he has more than one red heart container and a decent rate of fire.
Fire Mind: Explosions caused by tears can be used for healing
Kamikaze!: Allows immortality and infinite explosions for free.
Mom's Toenail: Becomes immune to the stomp.

This item is used in Challenge #23 (Blue Bomber).
Pyromania is an impulse control disorder in which individuals repeatedly fail to resist impulses to deliberately start fires.