Tech may refer to:
Items
- Technology, a passive item that replaces tears with lasers.
- Technology 2, a passive item that adds a continuous laser alongside Isaac's tears.
- Tech.5, a passive item that adds a random chance to fire lasers.
- The Ludovico Technique, a passive item that replaces tears with a controllable floating tear.
- Tech X, a passive item that replaces tears with laser rings.
- Technology Zero, a passive item that connects Isaac's tears with electricity.