Special Babies
These Babies have special effects that may help or hinder the player.
| Appearance | Name | Description |
|---|---|---|
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Spider Baby | Occasionally spawns a spider. |
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Love Baby | Drops a heart pickup when killed. Can also drop soul hearts. |
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Bloat Baby | Spawns with a Pretty Fly. |
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Water Baby | Explodes into tears when it dies. |
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Psy Baby | Spawns with homing tears. |
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Cursed Baby | Attracts enemies and enemy tears. |
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Troll Baby | Spawns troll bombs beneath itself at random times, and always spawns one upon death. |
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Ybab | Scrambles buttons associated with tear shot direction. |
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Cockeyed Baby | Shoots tears diagonally, similar to the effect of the R U a Wizard? pill. |
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Host Baby | Spawns one to three hostile Spiders upon death. |
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Lost Baby | Constantly bleeds small puddles of red creep which can damage enemies. Releases a larger puddle of creep upon death. Unlocked by defeating Mom's Heart with Isaac on Hard mode. |
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Cute Baby | Unlocked by defeating Mom's Heart with Maggy on Hard mode. |
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Crow Baby | Deals contact damage to enemies. Unlocked by defeating Mom's Heart with Eve on Hard mode. |
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Shadow Baby | Fires red blood shots and deals slightly more damage than other babies. Unlocked by defeating Mom's Heart with Judas on Hard mode. |
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Glass Baby | Drops a random pickup on death. Unlocked by defeating Mom's Heart with Cain on Hard mode. |
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Gold Baby | Drops 1-3 coins upon death. |
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Cy-Baby | Spawns with an effect similar to  Tech.5, randomly firing lasers alongside normal tears.
|
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Bean Baby | Farts when hit, like  The Black Bean effect.
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Mag Baby | Shiny silver baby that attracts coins. |
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Wrath Baby | Spawns a bomb pickup when killed. |
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Wrapped Baby | Explodes when hit. Unlocked by defeating Mom's Heart with Azazel on Hard mode. |
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Begotten Baby | Shoots large, slow moving tears that have a chance to cause fear. Unlocked by defeating Mom's Heart with Lazarus on Hard mode. |
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Dead Baby | Has a chance to spawn a Blue fly upon killing an enemy. Unlocked by defeating Mom's Heart with ??? on Hard mode. |
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Fighting Baby | Appears to throw its tears rather than crying them. Drops a heart pickup upon death. Unlocked by defeating Mom's Heart with Samson on Hard mode. |
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-0- Baby | Immune to all forms of damage. Leaving the game as this baby causes a different baby to spawn in its place. Unlocked by defeating Mom's Heart with The Lost on Hard mode. |
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Glitch Baby | Turns into a random baby at the start of each floor. Unlocked by defeating Mom's Heart with Eden on Hard mode. |
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Magnet Baby | Cannot fire tears. Can pick up items and open chests. |
| File:120 baby monochrome.png | Template:NoDLC Isaac 2 | Cannot fire tears. Can pick up items and open chests. |
Normal Babies
These Babies are purely cosmetic and do not have any special behaviors.
| Appearance | Name | Description |
|---|---|---|
| File:027 baby steven.png | Steven Baby | Reference to another one of Edmund McMillen's games, Time Fcuk. |
| File:028 baby monocle.png | Monocle Baby | A baby wearing a monocle. |
| File:029 baby belial.png | Belial Baby | A baby that looks like it used  The Book of Belial.
|
| File:030 baby monstro.png | Monstro Baby | A baby that looks like Monstro. |
| File:031 baby fez.png | Fez Baby | A baby wearing a fez, possibly a reference to the game, Fez. |
| File:032 baby meatboy.png | MeatBoy Baby | Reference to the titular character from Super Meat Boy. |
| File:033 baby skull.png | Skull Baby | A skeletal baby. |
| File:034 baby conjoined.png | Conjoined Baby | A baby with a conjoined twin who has a conjoined twin. |
| File:035 baby skinny.png | Skinny Baby | A baby that looks malnourished. |
| File:036 baby spider.png | Basic Spider Baby | A baby that has the characteristics of a spider. |
| File:037 baby shopkeeper.png | Shopkeeper Baby | A baby that looks like a shopkeeper. |
| File:038 baby fancy.png | Fancy Baby | A baby with a bowtie. |
| File:039 baby chubby.png | Chubby Baby | A chubby baby with three hairs. |
| File:040 baby cyclops.png | Cyclops Baby | A baby that looks like it has the item  Polyphemus.
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| File:041 baby isaac.png | Isaac Baby | A baby that looks like Isaac. |
| File:042 baby plug.png | Plug Baby | A baby that looks like an electrical outlet. |
| File:043 baby drool.png | Drool Baby | A baby that is drooling. |
| File:044 baby wink.png | Wink Baby | A baby that is winking. |
| File:045 baby pox.png | Pox Baby | A baby that has smallpox or chickenpox. |
| File:046 baby onion.png | Onion Baby | A baby with a head that looks like the item  The Sad Onion.
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| File:047 baby zipper.png | Zipper Baby | A pale baby with a zipper on its torso. |
| File:048 baby buckteeth.png | Buckteeth Baby | A baby with buckteeth. |
| File:049 baby beard.png | Beard Baby | A bearded baby. |
| File:050 baby hanger.png | Hanger Baby | A baby that appears to have the item  Wire Coat Hanger.
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| File:051 baby vampire.png | Vampire Baby | A vampiric baby. |
| File:052 baby tilt.png | Tilt Baby | A baby whose face is tilted. |
| File:053 baby bawl.png | Bawl Baby | A baby who looks to be crying more than usual. |
| File:054 baby lemon.png | Lemon Baby | A baby with a lemon head. |
| File:055 baby tooth.png | Tooth Baby | A baby with one tooth. |
| File:056 baby haunt.png | Haunt Baby | A ghostly baby. |
| File:057 baby bigeyes.png | Big Eyes Baby | A baby with big eyes. |
| File:058 baby sleep.png | Sleep Baby | A sleeping baby. |
| File:059 baby zombie.png | Zombie Baby | An undead baby. |
| File:060 baby goat.png | Goat Baby | A baby that looks like a goat. |
| File:061 baby butthole.png | Butthole Baby | A baby with an anus for a face. |
| File:062 baby eyepatch.png | Eye Patch Baby | A baby that looks remarkably similar to Cain. |
| File:063 baby bloodeyes.png | Blood Eyes Baby | A baby who is crying blood. |
| File:064 baby mustache.png | Mustache Baby | A baby with a mustache. |
| File:065 baby spittle.png | Spittle Baby | A baby who seems to be drooling. |
| File:066 baby brain.png | Brain Baby | A baby that looks like it has the item  The Mind.
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| File:067 baby threeeyes.png | 3 Eyes Baby | A baby with three eyes. |
| File:068 baby viridian.png | Viridian Baby | Reference to the VVVVVV character of the same name, similar to the VVVVVV baby below. |
| File:069 baby blockhead.png | Blockhead Baby | A baby with a blocky head. |
| File:070 baby worm.png | Worm Baby | A baby that looks like  Little Chubby.
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| File:071 baby lowface.png | Lowface Baby | A baby with a lowered face. |
| File:072 baby alienhominid.png | Alien Hominid Baby | Reference to the game Alien Hominid by The Behemoth. |
| File:073 baby bomb.png | Bomb Baby | A baby with a bomb for a head. |
| File:074 baby video.png | Video Baby | Reference to Commander Video, the main character of the BIT.TRIP series. |
| File:075 baby parasite.png | Parasite Baby | A baby that seems to be a parasite. |
| File:076 baby derp.png | Derp Baby | A reference to the internet meme, DERP. |
| File:077 baby lobotomy.png | Lobotomy Baby | A baby who seems to have been lobotomized. |
| File:078 baby choke.png | Choke Baby | A baby that looks to have been choked to death. |
| File:079 baby scream.png | Scream Baby | Reference to Edvard Munch's "The Scream". |
| File:080 baby gurdy.png | Gurdy Baby | A baby that looks like Gurdy. |
| File:081 baby ghoul.png | Ghoul Baby | A baby that has large red eyes and fangs. |
| File:082 baby goatee.png | Goatee Baby | A baby with a goatee. |
| File:083 baby shades.png | Shades Baby | A baby with sunglasses. |
| File:084 baby statue.png | Statue Baby | A baby that is composed of stone. |
| File:085 baby bloodsucker.png | Bloodsucker Baby | A baby with blood coming out of its mouth and eyes. |
| File:086 baby bandaid.png | Bandaid Baby | A baby with a bandage on its head. |
| File:087 baby eyebrows.png | Eyebrows Baby | A baby with thick eyebrows. |
| File:088 baby nerd.png | Nerd Baby | A baby with square glasses. |
| File:089 baby boss.png | Boss Baby | Based on Newgrounds' Agnry Faic. |
| File:090 baby turd.png | Turd Baby | A baby composed of poop. |
| File:091 baby o.png | O Baby | A baby making an "O" face. |
| File:092 baby squareeyes.png | Square Eyes Baby | A baby with square eyes. |
| File:093 baby teeth.png | Teeth Baby | A baby with noticeable teeth. |
| File:094 baby frown.png | Frown Baby | A frowning baby. |
| File:095 baby tongue.png | Tongue Baby | A baby whose tongue is sticking out. |
| File:096 baby halfhead.png | Half Head Baby | A baby with the top half of its head missing. |
| File:097 baby makeup.png | Makeup Baby | A baby wearing makeup. |
| File:098 baby ed.png | Ed Baby | Appears similar to Edmund McMillen, the creator of the game. |
| File:099 baby d.png | D Baby | Appears similar to Danielle, Edmund's wife. |
| File:100 baby guppy.png | Guppy Baby | A baby that looks like Edmund's first cat, Guppy. |
| File:101 baby puke.png | Puke Baby | A baby that's vomiting. |
| File:102 baby dumb.png | Dumb Baby | A smiling blue baby. |
| File:103 baby lipstick.png | Lipstick Baby | A baby wearing an excess amount of lipstick. |
| File:104 baby aether.png | Aether Baby | Reference to Aether, another one of Edmund McMillen's games. |
| File:105 baby brownie.png | Brownie Baby | Reference to Brownie, a character from Super Meat Boy. |
| File:106 baby vvvvvv.png | VVVVVV Baby | Reference to Captain Viridian, the main character of VVVVVV. |
| File:107 baby nosferatu.png | Nosferatu Baby | A reference to the movie, Noseferatu. |
| File:108 baby pubic.png | Pubic Baby | A baby with the cosmetic effect of the pill Puberty. |
| File:109 baby eyemouth.png | Eyemouth Baby | A baby with an eye in its mouth. |
| File:110 baby weirdo.png | Weirdo Baby | A frowning blue baby. |
| File:111 baby v.png | V Baby | A baby with a red "V" on its head. |
| File:112 baby strangemouth.png | Strange Mouth Baby | A baby with the ":3" face. |
| File:113 baby masked.png | Masked Baby | A baby with a black mask and red eyes. |
| File:114 baby cyber.png | Cyber Baby | A reference to the cyber men from Doctor Who. |
| File:115 baby axewound.png | Axe Wound Baby | Fires tears from its wound. |
| File:116 baby statue.png | Statue Baby | A petrified baby. |
| File:117 baby grin.png | Grin Baby | A grinning baby. |
| File:118 baby upset.png | Upset Baby | A baby who looks upset. |
| File:119 baby plastic.png | Plastic Baby | A baby that looks extraterrestrial. |
| File:120 baby monochrome.png | Monochrome Baby | Possibly a reference to the character Monoko from Yume Nikki. |
| File:121 baby onetooth.png | One Tooth Baby | A baby with a single tooth. |
| File:122 baby tusks.png | Tusks Baby | A baby with two large tusks. |
| File:123 baby hopeless.png | Hopeless Baby | A black depressed baby. |
| File:124 baby bigmouth.png | Big Mouth Baby | A baby with a big mouth. |
| File:125 baby peeeyes.png | Pee Eyes Baby | A baby with urine in its eyes. |
| File:126 baby earwig.png | Earwig Baby | A baby that looks like an earwig. |
| File:127 baby ninkumpoop.png | Ninkumpoop Baby | A baby that appears to be yawning. |
| File:128 baby strangeshape.png | Strange Shape Baby | A baby with an almond shaped head. |
| File:129 baby bugeyed.png | Bugeyed Baby | A baby with bugeyes. |
| File:130 baby freaky.png | Freaky Baby | A baby with a large mouth and sharp teeth. |
| File:131 baby crooked.png | Crooked Baby | A baby whose eyes are off center. |
| File:132 baby spiderlegs.png | Spider Legs Baby | A baby that looks like a spider. |
| File:133 baby smiling.png | Smiling Baby | A smiling baby. |
| File:134 baby tears.png | Tears Baby | A crying baby. |
| File:135 baby bowling.png | Bowling Baby | A brown baby. |
| File:136 baby mohawk.png | Mohawk Baby | A baby with a mohawk. |
| File:137 baby rottenmeat.png | Rotten Meat Baby | A baby that appears to be a rotten version of Meatboy. |
| File:138 baby noarms.png | No Arms Baby | A baby with no arms. |
| File:139 baby twin2.png | Twin Baby 2 | A baby that has a blue bow. |
| File:140 baby uglygirl.png | Ugly Girl Baby | A yellow baby with a pink bow. |
| File:141 baby chompers.png | Chompers Baby | A baby that bears a slight resemblance to Scolex. |
| File:142 baby camillojr.png | Camillo Jr Baby | A baby that looks like the enemy Camillo Jr. |
| File:143 baby eyeless.png | Eyeless Baby | A baby with no eyes. |
| File:144 baby sloppy.png | Sloppy Baby | A baby with a crooked mouth. |
| File:145 baby bluebird.png | Bluebird Baby | A blue baby with wings. |
| File:146 baby fat.png | Fat Baby | A baby that looks like Gluttony. |
| File:147 baby butterfly.png | Butterfly Baby | Appears to look like a winged Pikmin from Pikmin 3. |
| File:148 baby goggles.png | Goggles Baby | A baby with goggles. |
| File:149 baby apathetic.png | Apathetic Baby | A baby that seems to be bored. |
| File:150 baby cape.png | Cape Baby | A baby with a cape. |
| File:151 baby sorrow.png | Sorrow Baby | A blue baby with a grimace on its face. |
| File:152 baby rictus.png | Rictus Baby | A baby with a frown of pain on its face. |
| File:153 baby awaken.png | Awaken Baby | A baby with closed eyes. |
| File:154 baby puff.png | Puff Baby | Reference to Kirby. |
| File:155 baby attractive.png | Attractive Baby | Another baby with the ":3" face. |
| File:156 baby pretty.png | Pretty Baby | A baby with eyeshadow. |
| File:157 baby crackedinfamy.png | Cracked Infamy Baby | A baby with a cracked Infamy mask. |
| File:158 baby distended.png | Distended Baby | A baby with twisted arms. |
| File:159 baby mean.png | Mean Baby | A green baby with a grumpy look. |
| File:160 baby digital.png | Digital Baby | A green baby that has the static T.V. effect. |
| File:161 baby helmet.png | Helmet Baby | A baby with a helmet. |
| File:162 baby blackeye.png | Black Eye Baby | A baby with a black eye. |
| File:163 baby lights.png | Lights Baby | A baby with white eyes. |
| File:164 baby spike.png | Spike Baby | A baby with a spike on its head. |
| File:165 baby worry.png | Worry Baby | A baby with blue skin and a frown. |
| File:166 baby ears.png | Ears Baby | A baby with animal-like ears. |
| File:167 baby funeral.png | Funeral Baby | A baby with a tuxedo. |
| File:168 baby libra.png | Libra Baby | A baby that looks like it has the item  Libra.
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| File:169 baby gappy.png | Gappy Baby | A angry baby with red eyes. |
| File:170 baby sunburn.png | Sunburn Baby | A red baby. |
| File:171 baby atepoop.png | Ate Poop Baby | A baby who ate poop. |
| File:172 baby electris.png | Electric Baby | Reference to Pikachu from Pokémon. |
| File:173 baby bloodhole.png | Blood Hole Baby | A baby with a bloody anus for a face. |
| File:174 baby transforming.png | Transforming Baby | Reference to Optimus Prime from Transformers. |
| File:175 baby aban.png | Aban Baby | Reference to Aban Hawkins from 1001 Spikes. |
| File:176 baby bandagegirl.png | Bandage Girl Baby | Reference to Bandage Girl from Super Meat Boy. |
| File:177 baby piecea.png | Piece A Baby | Reference to Tetris. |
| File:178 baby pieceb.png | Piece B Baby | Reference to Tetris. |
| File:179 baby spelunker.png | Spelunker Baby | Reference to the Spelunker from Spelunky. |
| File:180 baby frog.png | Frog Baby | A baby that looks like a frog. |
| File:181 baby crook.png | Crook Baby | A baby with a bandit's eye mask. |
| File:182 baby don.png | Don Baby | Reference to Donatello from Teenage Mutant Ninja Turtles. |
| File:183 baby web.png | Web Baby | A baby with strands of spider silk stuck on it. |
| File:184 baby faded.png | Faded Baby | A baby that appears to be phasing out of existence. |
| File:185 baby sick.png | Sick Baby | A sickly baby. |
| File:186 baby drfetus.png | Dr Fetus Baby | Reference to Dr. Fetus from Super Meat Boy. |
| File:187 baby spectral.png | Spectral Baby | A baby that is translucent in appearance. |
| File:188 baby redskeleton.png | Red Skeleton Baby | A reference to the Red Skeleton enemy from Castlevania. |
| File:189 baby skeleton.png | Skeleton Baby | A reference to the Skeleton enemy from Castlevania. |
| File:190 baby jammies.png | Jammies Baby | A baby with pajamas. |
| File:191 baby newjammies.png | New Jammies Baby | A baby with red pajamas. |
| File:192 baby cold.png | Cold Baby | A baby with a snowman appearance. |
| File:193 baby oldman.png | Old Man Baby | A baby that appears to look like an old man. |
| File:194 baby spooked.png | Spooked Baby | A scared baby. |
| File:195 baby nice.png | Nice Baby | A baby with a neutral expression. |
| File:196 baby dots.png | Dots Baby | A baby with blood splattered on it. |
| File:197 baby peeling.png | Peeling Baby | A baby whose skull is exposed. |
| File:198 baby smallface.png | Small Face Baby | A baby with an abnormally small face. |
| File:199 baby good.png | Good Baby | A happy baby with blonde hair. |
| File:200 baby blindfold.png | Blindfold Baby | A baby with a blindfold. |
| File:201 baby pipe.png | Pipe Baby | A baby with a pipe stuck in its head. |
| File:202 baby dented.png | Dented Baby | A baby with a dented head. |
