This article is about The Mark, not to be confused with Marked.
The Mark is a passive item.
Effects[ | ]
Grants one Soul Heart.- Grants one Black Heart.
- +1 damage.
- +0.2 speed.
- This item belongs to the Leviathan set. Collecting three items from this set will transform Isaac into Leviathan.
Grants one 
Grants one 
This item belongs to the 
In-game Footage[ | ]
Trivia[ | ]
- The Mark refers to the Mark of the Beast in the end of times prophecies (3 6's arranged in a triskelion). Without this mark, one would not be allowed to buy or sell.
- While The Mark's icon shows the 6's facing towards the center, on Isaac's forehead the symbol appears with the 6's facing outwards.
- Loki has the Mark of the Beast on his forehead.
 The Binding of Isaac: Rebirth
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