The Tank

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The Tank is Challenge #5. This challenge stars Magdalene who starts with Bucket of Lard, Infamy, Yum Heart, and Thunder Thighs. The goal is to defeat Mom. This Challenge is unlocked when Magdalene is unlocked.

Difficulty

This challenge features a very slow character and thus is more difficult. The Thunder Thighs effect can cause unwanted results when not paying attention, such as setting off Bomb Rocks or creating new monsters to fight.

Strategy

You start with 7 heart containers, 5 1/2 of which are full. This will come in handy as you will likely take more damage.
The Thunder Thighs effect can easily give access to chests and other items trapped behind rocks. This will leave bombs more available for seeking secret rooms or combat. Pills can be obtained from mushrooms, which may provide a much needed Speed Up, but be cautious, as mushrooms can spawn poisonous clouds when destroyed.
- Completing Aprils Fool makes this challenge a tad easier, as it makes Magdalene spawn with a Speed Up pill, counteracting the heavy speed reduction from the challenge items and easily identifying eventual future Speed Up pills.
It is worth destroying as many rocks as possible, as there is a chance of finding a trapdoor. This can lead the player to a Crawl Space or Black Market, thereby allowing the player to obtain valuable items despite the lack of Treasure Rooms.
The high amount of health you start with makes it easier to make deals with the devil without harsh consequences. If you get the chance to gain flight, such as the Lord of the Pit or Spirit of the Night, it can give increased mobility in the lower levels.
Infamy gives a chance to ignore shots, but it's best not to rely on it.

Unlockable Achievements

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Bugs

Bug!	Sometimes, when using a Pill at the same time you touch the trophy, the pop up message won't appear and you won't unlock Rune of Ansuz.^{[citation needed]}