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Font TeamMeat T.pngFont TeamMeat r.pngFont TeamMeat i.pngFont TeamMeat s.pngFont TeamMeat a.pngFont TeamMeat g.pngFont TeamMeat i.pngFont TeamMeat o.pngFont TeamMeat n.png
Item icon
Item altar
Table dividing line 1.png
Character appearance
Tear appearance
Table dividing line 2.png
Angel Room Angel Room
Greed mode only Angel Room Angel Room
Table dividing line 3.png
(page 5, column 8, row 3)
Trisagion Take 25 items from Angel roomsTrisagionTrisagion
Added in Afterbirth †

Trisagion is an unlockable passive item added in Booster Pack #4.

Effects[edit | edit source]

  • Tears are replaced with piercing white blasts of light.
    • Blasts deal 33% of the regular tear damage but can hit the same enemy multiple times.
    • Blasts do not knockback enemies.

Notes[edit | edit source]

  • Since the blasts can strike one enemy multiple times, low shot speed can be very beneficial whereas high shot speed may lower effective damage.
    • Walking backward while firing can allow tears to move slower, making it useful for increasing damage output.

Synergies[edit | edit source]

  • 8 Inch Nails 8 Inch Nails / Blister BlisterTrinket Blister icon.pngIncreases knockback of tears. / Pisces Pisces: Adds knockback to blasts, which can not only significantly repel enemies when used correctly, it can deal a high amount of damage to enemies unable to escape the knockback.
  • Chocolate Milk Chocolate Milk: Fully charged Trisagion blasts deal 4 times more damage, exceeding Isaac's base damage.
  • Godhead Godhead: Although the damaging aura isn't visible, it still exists and is not affected by Trisagion's damage reduction.
  • Guppy (Transformation): As it hits multiple times, it spawns multiple flies per tear making it very strong.
  • Haemolacria Haemolacria: Both Trisagion and Haemolacria fire at the same time, Haemolacria does not keep spectral tears despite its tears sprite change but the arced tear keeps piercing.
  • Ipecac Ipecac: Beams will now travel through obstacles and maintain their piercing effect dealing 33% of regular damage to enemies they come in contact with, but won't explode on hit. The Ipecac explosion will happen once the beam runs out of range or hits a wall and will deal damage equal to Isaac's damage.
  • The Ludovico Technique The Ludovico Technique: The beam becomes controllable, still dealing reduced damage but at a very high rate.
  • My Reflection My Reflection: In addition to the usual effect, lengthens the Trisagion blasts into short flexible beams for a much larger damage-dealing area.
  • Mysterious Liquid Mysterious Liquid: Causes a large trail of creep. The effect stacks, which causes heavy damage (even to Hush).
  • Proptosis Proptosis: Base damage is doubled and beam damage is boosted to about 65%. Blasts lose no power as they travel further, though the tips of the blasts deal very slightly less damage.

Interactions[edit | edit source]

  • Azazel: Azazel's short-range Brimstone overrides Trisagion.
  • Brimstone Brimstone: Overrides Trisagion.
  • Cricket's Body Cricket's Body/Compound Fracture Compound Fracture/The Parasite The Parasite: Split blasts are not generated on hitting enemies, only on obstacles and walls, as well as floors for Cricket's Body.
  • Dead Eye Dead Eye: Overridden by Trisagion.
  • Dr. Fetus Dr. Fetus: Overrides Trisagion.
  • Epic Fetus Epic Fetus: Overrides Trisagion.
  • Eye of Belial Eye of Belial: Overridden by Trisagion.
  • Euthanasia Euthanasia: Overridden by Trisagion.
  • Flat Stone Flat Stone: Blasts continually disappear and reappear as they "bounce". The bounces deal 25% splash damage based on Isaac's base rating, but the blasts cannot do their damage while they're disappearing, leading to an overall reduced efficiency.
  • Holy Light Holy Light: Overridden by Trisagion.
  • Jacob's Ladder Jacob's Ladder: Electric arcs are not generated on hitting enemies, only on obstacles and walls.
  • Lachryphagy Lachryphagy: The blasts will slow down and float like Lachryphagy tears and eventually burst, but can not consume each other.
  • A Lump of Coal A Lump of Coal: Nearly no effect; increases damage by around 5% when the hit is dealt by the tip of the blast.
    • A Lump of Coal + My Reflection: As the beam is longer, the amount of extra damage at the tip can be up to around 50%.
  • Mom's Knife Mom's Knife: Overrides Trisagion.
  • Multidimensional Baby Multidimensional Baby: The baby cannot duplicate Trisagion blasts.
  • Nose Goblin Nose GoblinTrinket Nose Goblin icon.pngChance to fire a booger that sticks to enemies and deals damage over time.: Overridden by Trisagion.
  • Parasitoid Parasitoid: Overridden by Trisagion.
  • Pop! Pop!: The blasts will slow down and float like Pop! tears, but will not bounce off each other.
  • Sinus Infection Sinus Infection: Overridden by Trisagion.
  • Tech X Tech X: Overrides Trisagion.
  • Technology Technology: Overrides Trisagion.
  • Technology Zero Technology Zero: Unless Isaac has shooting familiars, Technology Zero will not function. Familiars' tears will be connected to the blasts with electricity, however.

In-game Footage[edit | edit source]

Trivia[edit | edit source]

  • Trisagion is based on this Steam Workshop item by x Wyvern x and TRPG, originally known as Lightshot.
  • The name is a reference to one of the oldest Christian hymns.

Gallery[edit | edit source]

Collectible Moving Box icon.png Booster Packs Collectible Moving Box icon.png
  • Collectible Angry Fly icon.png
  • Collectible Black Hole icon.png
  • Collectible Bozo icon.png
  • Collectible Broken Modem icon.png
  • Collectible Mystery Gift icon.png
  • Sprinkler Icon.png
  • Collectible Fast Bombs icon.png
  • Collectible Buddy in a Box icon.png
  • Collectible Lil Delirium icon.png
  • HairpinHairpinFully recharges Isaac's active item upon entering a boss fight.
  • Wooden CrossWooden CrossGrants a Holy Mantle shield upon entering a new floor, which protects against one hit of damage.
  • Butter!Butter!Using an active item will drop it onto a pedestal on the ground. Taking damage may result in dropping a passive item.
  • Huge GrowthHuge GrowthMakes Isaac large for the current room, increasing his range and damage.
  • Ancient RecallAncient RecallSpawns 3 random cards.
  • Era WalkEra WalkFor the current room, enemies are slowed, Isaac's speed is increased, and his shot speed is decreased.
  • Collectible Jumper Cables icon.png
  • Collectible Coupon icon.png
  • Telekinesis Icon.png
  • Collectible Moving Box icon.png
  • Technology Zero Icon.png
  • Collectible Leprosy icon.png
  • Filigree FeatherFiligree FeatherAngels drop items instead of key pieces when defeated.
  • Dressing Table.png
  • 7 Seals icon.png
  • Collectible Mr. ME! icon.png
  • Collectible Angelic Prism icon.png
  • Collectible Pop! icon.png
  • Door StopDoor StopThe last door Isaac went through stays open, allowing him to leave the room even if enemies are in it.
  • Collectible Death's List icon.png
  • Collectible Haemolacria icon.png
  • Collectible Lachryphagy icon.png
  • Collectible Trisagion icon.png
  • Collectible Schoolbag icon.png
  • Extension CordExtension CordBeams of yellow electricity flow between Isaac and his familiars, damaging any enemies between them.
  • Cross Grimace.png
  • Fistuloid.png
  • Gush.png
  • Soul Sucker.png
  • Tar Boy.png
  • Tube Worm.png
  • Collectible Blanket icon.png
  • Collectible Sacrificial Altar icon.png
  • Collectible Lil Spewer icon.png
  • Collectible Marbles icon.png
  • Collectible Mystery Egg icon.png
  • Collectible Flat Stone icon.png
  • Collectible Marrow icon.png
  • Slipped Rib Icon.png
  • Collectible Hallowed Ground icon.png
  • Collectible Pointy Rib icon.png
  • Collectible Book of the Dead icon.png
  • Collectible Dad's Ring icon.png
  • Collectible Divorce Papers icon.png
  • Collectible Jaw Bone icon.png
  • Collectible Brittle Bones icon.png
  • Collectible Broken Shovel 1 icon.png
  • Collectible Broken Shovel 2 icon.png
  • Collectible Mom's Shovel icon.png
  • Rotten PennyRotten PennySpawns a blue fly every time a coin is picked up.
  • Baby-BenderBaby-BenderGrants Isaac's familiars homing shots.
  • Finger BoneFinger BoneGrants a chance to gain a bone heart upon taking damage.
  • The Forgotten App.png
  • Crispy.png
  • Cross Stoney.png
  • Dank Charger.png
  • Leper.png
  • Leper Flesh.png
  • Mr. Mine.png
  • Mr. Red Maw.png
  • Boss The Matriarch.png
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