Binding of Isaac: Rebirth Wiki
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(in Afterbirth † and Repentance)

Trisagion is an unlockable passive item added in Booster Pack #4.

Effects

  • Tears are replaced with piercing white blasts of light.
    • Blasts deal 33% of regular tear damage, but can hit the same enemy multiple times.
    • Blasts do not knock back enemies.

Notes

  • Since the blasts can strike one enemy multiple times, low shot speed can be very beneficial whereas high shot speed may lower effective damage.
    • Walking backwards while firing can allow tears to move slower, making it useful for increasing damage output.

Synergies

  • Collectible 8 Inch Nails icon8 Inch Nails / BlisterBlister / Collectible Pisces iconPisces: Adds knockback to blasts, which can not only significantly repel enemies when used correctly, it can deal a high amount of damage to enemies unable to escape the knockback.
  • Collectible Chocolate Milk iconChocolate Milk: Fully charged Trisiagon blasts deal 4 times more damage, exceeding Isaac's base damage.
  • Collectible Godhead iconGodhead: Although the damaging aura isn't visible, it still exists and is not affected by Trisagion's damage reduction.
  • Guppy (Transformation): As it hits multiple times, it spawns multiple flies per tear making it very strong.
  • Homing tears: The blasts can deal extra damage as they remain in contact with enemies longer.
  • Collectible Ipecac iconIpecac: Ipecac's damage boost applies; the light beam causes explosions dealing full damage when it impacts something or runs out of range. Use with caution. Having Collectible Pyromaniac iconPyromaniac or Collectible Host Hat iconHost Hat is recommended.
  • Collectible The Ludovico Technique iconThe Ludovico Technique: The beam becomes controllable, still dealing reduced damage but at very high rate.
  • Collectible My Reflection iconMy Reflection: In addition to the usual effect, lengthens the Trisagion blasts into short flexible beams for a much larger damage-dealing area.
  • Collectible Mysterious Liquid iconMysterious Liquid: Causes a large trail of creep. The effect stacks, which causes heavy damage (even to Hush).
  • Collectible Proptosis iconProptosis: Base damage is doubled and beam damage is boosted to about 65%. Blasts lose no power as they travel further, though the tips of the blasts deal very slightly less damage.
    • Proptosis + Collectible My Reflection iconMy Reflection: As the beams are longer, the damage decrease at the tips is more noticeable, but the net effect is still a large boost.

Interactions

  • Azazel: Azazel's short range Brimstone overrides Trisagion.
  • Collectible Brimstone iconBrimstone: Overrides Trisagion.
  • Collectible Cricket's Body iconCricket's Body/Collectible Compound Fracture iconCompound Fracture/Collectible The Parasite iconThe Parasite: Split blasts are not generated on hitting enemies, only on obstacles and walls, as well as floors for Cricket's Body.
  • Collectible Dead Eye iconDead Eye: Overridden by Trisagion.
  • Collectible Dr. Fetus iconDr. Fetus: Overrides Trisagion.
  • Collectible Epic Fetus iconEpic Fetus: Overrides Trisagion.
  • Collectible Euthanasia iconEuthanasia: Blasts will occasionally do triple damage, but will not instantly kill enemies or burst.
  • Collectible Eye of Belial iconEye of Belial: Overridden by Trisagion.
  • Collectible Flat Stone iconFlat Stone: Blasts continually disappear and reappear as they "bounce". The bounces deal 25% splash damage based on Isaac's base rating, but the blasts cannot do their damage while they're disappearing, leading to an overall reduced effeciency.
  • Collectible Haemolacria iconHaemolacria: Functions otherwise as normal, but all blasts deal the same reduced damage.
  • Collectible Holy Light iconHoly Light: Overridden by Trisagion.
  • Collectible Jacob's Ladder iconJacob's Ladder: Electric arcs are not generated on hitting enemies, only on obstacles and walls.
  • Collectible Lachryphagy iconLachryphagy: The blasts will slow down and float like Lachryphagy tears and eventually burst, but can not consume each other.
  • Collectible A Lump of Coal iconA Lump of Coal: Nearly no effect; increases damage by around 5% when the hit is dealt by the tip of the blast.
    • A Lump of Coal + Collectible My Reflection iconMy Reflection: As the beam is longer, the amount of extra damage at the tip can be up to around 50%.
  • Collectible Mom's Knife iconMom's Knife: Overrides Trisagion.
  • Collectible Multidimensional Baby iconMultidimensional Baby: The baby cannot duplicate Trisagion blasts.
  • Collectible Parasitoid iconParasitoid: Overridden by Trisagion.
  • Collectible Pop! iconPop!: The blasts will slow down and float like Pop! tears, but will not bounce off each other.
  • Collectible Rubber Cement iconRubber Cement: The blasts continue to pierce enemies, but will bounce off walls and obstacles.
  • Collectible Sinus Infection iconSinus Infection: Overridden by Trisagion.
  • Collectible Tech X iconTech X: Overrides Trisagion.
  • Collectible Technology iconTechnology: Overrides Trisagion.
  • Collectible Technology Zero iconTechnology Zero: Unless Isaac has shooting familiars, Technology Zero will not function. Familiars' tears will be connected to the blasts with electricity, however.

In-game Footage

Trivia

  • Trisagion is based on this Steam Workshop item by x Wyvern x.
  • The name is a reference to one of the oldest christian hymns.

Gallery


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